Cargando…
PPP2R2D suppresses IL-2 production and Treg function
Protein phosphatase 2A is a ubiquitously expressed serine/threonine phosphatase that comprises a scaffold, a catalytic, and multiple regulatory subunits and has been shown to be important in the expression of autoimmunity. We considered that a distinct subunit may account for the decreased productio...
Autores principales: | Pan, Wenliang, Sharabi, Amir, Ferretti, Andrew, Zhang, Yinfeng, Burbano, Catalina, Yoshida, Nobuya, Tsokos, Maria G., Tsokos, George C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566706/ https://www.ncbi.nlm.nih.gov/pubmed/32897879 http://dx.doi.org/10.1172/jci.insight.138215 |
Ejemplares similares
-
Phosphofructokinase P fine-tunes T regulatory cell metabolism, function, and stability in systemic autoimmunity
por: Scherlinger, Marc, et al.
Publicado: (2022) -
Amino Acid Metabolism in Lupus
por: Kono, Michihito, et al.
Publicado: (2021) -
Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells
por: Li, Hao, et al.
Publicado: (2020) -
The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity
por: Lieberman, Linda A., et al.
Publicado: (2010) -
A serine/threonine phosphatase, PP2A, controls autoimmunity
por: Tsokos, George C
Publicado: (2014)