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Design, synthesis, and biological evaluation of N-arylpiperazine derivatives as interferon inducers
Type I Interferon (IFN) signaling plays an important role in the immune defense system against virus infection and in the innate immune response, thus IFNs are widely used as anti-viral agents and treatment for immune disorder or cancer. However, there is a growing demand for novel small-molecule IF...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566768/ https://www.ncbi.nlm.nih.gov/pubmed/33075488 http://dx.doi.org/10.1016/j.bmcl.2020.127613 |