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The development of colitis in Il10(−/−) mice is dependent on IL-22
Mice deficient in the IL-10 pathway are the most widely-used models of intestinal immunopathology.IL-17A is strongly implicated in gut disease in mice and humans, but conflicting evidence has drawn IL-17’s role in the gut into question.IL-22 regulates antimicrobial and repair activities of intestina...
Autores principales: | Gunasekera, Dilini C., Ma, Jinxia, Vacharathit, Vimvara, Shah, Palak, Ramakrishnan, Amritha, Uprety, Priyanka, Shen, Zeli, Sheh, Alexander, Brayton, Cory F., Whary, Mark T., Fox, James G., Bream, Jay H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566780/ https://www.ncbi.nlm.nih.gov/pubmed/31932715 http://dx.doi.org/10.1038/s41385-019-0252-3 |
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