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Monoclonal therapy against calcitonin gene-related peptide lowers hyperglycemia and adiposity in type 2 diabetes mouse models

OBJECTIVE: Calcitonin Gene-Related Peptide α (CGRPα) is a multifunctional neuropeptide found in the central and peripheral nervous system with cardiovascular, nociceptive, and gastrointestinal activities. CGRPα has been linked to obesity and insulin secretion but the role of this circulating peptide...

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Detalles Bibliográficos
Autores principales: Halloran, Jonathan, Lalande, Alexandre, Zang, Mandy, Chodavarapu, Harshita, Riera, Céline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566843/
https://www.ncbi.nlm.nih.gov/pubmed/33089134
http://dx.doi.org/10.1016/j.metop.2020.100060