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Monoclonal therapy against calcitonin gene-related peptide lowers hyperglycemia and adiposity in type 2 diabetes mouse models
OBJECTIVE: Calcitonin Gene-Related Peptide α (CGRPα) is a multifunctional neuropeptide found in the central and peripheral nervous system with cardiovascular, nociceptive, and gastrointestinal activities. CGRPα has been linked to obesity and insulin secretion but the role of this circulating peptide...
Autores principales: | Halloran, Jonathan, Lalande, Alexandre, Zang, Mandy, Chodavarapu, Harshita, Riera, Céline E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566843/ https://www.ncbi.nlm.nih.gov/pubmed/33089134 http://dx.doi.org/10.1016/j.metop.2020.100060 |
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