Hypermethylation and reduced expression of Gtl2, Rian and Mirg at the Dlk1-Dio3 imprinted locus as a marker for poor developmental potential of mouse embryonic stem cells

Mouse embryonic stem cells (ESCs) have played a crucial role in biomedical research where they can be used to elucidate gene function through the generation of genetically modified mice. A critical requirement for the success of this technology is the ability of ESCs to contribute to viable chimaera...

Descripción completa

Detalles Bibliográficos
Autores principales: Schacker, Maria, Cheng, Yi-Han, Eckersley-Maslin, Melanie, Snaith, Richard Michael, Colledge, William Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567021/
https://www.ncbi.nlm.nih.gov/pubmed/32822966
http://dx.doi.org/10.1016/j.scr.2020.101931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567021/
https://www.ncbi.nlm.nih.gov/pubmed/32822966
http://dx.doi.org/10.1016/j.scr.2020.101931

Ejemplares similares