Therapeutic Potential of Autophagy in Glioblastoma Treatment With Phosphoinositide 3-Kinase/Protein Kinase B/Mammalian Target of Rapamycin Signaling Pathway Inhibitors

Glioblastoma (GB) is the most malignant and aggressive form of brain tumor, characterized by frequent hyperactivation of the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway. PI3K/AKT/mTOR inhibitors have a promising clinical efficacy the...

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Detalles Bibliográficos
Autores principales: Xia, Qin, Xu, Mengchuan, Zhang, Pei, Liu, Liqun, Meng, Xinyi, Dong, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567033/
https://www.ncbi.nlm.nih.gov/pubmed/33123479
http://dx.doi.org/10.3389/fonc.2020.572904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567033/
https://www.ncbi.nlm.nih.gov/pubmed/33123479
http://dx.doi.org/10.3389/fonc.2020.572904

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