A Qualitative Change in the Transcriptome Occurs after the First Cell Cycle and Coincides with Lumen Establishment during MDCKII Cystogenesis

Madin-Darby canine kidney II (MDCKII) cells are widely used to study epithelial morphogenesis. To better understand this process, we performed time course RNA-seq analysis of MDCKII 3D cystogenesis, along with polarized 2D cells for comparison. Our study reveals a biphasic change in the transcriptom...

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Detalles Bibliográficos
Autores principales: Wang, Tianfang, Kwon, Sang-Ho, Peng, Xiao, Urdy, Severine, Lu, Zefu, Schmitz, Robert J., Dalton, Stephen, Mostov, Keith E., Zhao, Shaying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567049/
https://www.ncbi.nlm.nih.gov/pubmed/33089114
http://dx.doi.org/10.1016/j.isci.2020.101629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567049/
https://www.ncbi.nlm.nih.gov/pubmed/33089114
http://dx.doi.org/10.1016/j.isci.2020.101629

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