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Non-junctional role of Cadherin3 in cell migration and contact inhibition of locomotion via domain-dependent, opposing regulation of Rac1

Classical cadherins are well-known adhesion molecules responsible for physically connecting neighboring cells and signaling this cell–cell contact. Recent studies have suggested novel signaling roles for “non-junctional” cadherins (NJCads); however, the function of cadherin signaling independent of...

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Detalles Bibliográficos
Autores principales: Ichikawa, Takehiko, Stuckenholz, Carsten, Davidson, Lance A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567069/
https://www.ncbi.nlm.nih.gov/pubmed/33060598
http://dx.doi.org/10.1038/s41598-020-73862-y