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Redundant type II cadherins define neuroepithelial cell states for cytoarchitectonic robustness

Individual cell shape and integrity must precisely be orchestrated during morphogenesis. Here, we determine function of type II cadherins, Cdh6, Cdh8, and Cdh11, whose expression combinatorially demarcates the mouse neural plate/tube. While CRISPR/Cas9-based single type II cadherin mutants show no o...

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Detalles Bibliográficos
Autores principales: Hiraga, Kou, Inoue, Yukiko U., Asami, Junko, Hotta, Mayuko, Morimoto, Yuki, Tatsumoto, Shoji, Hoshino, Mikio, Go, Yasuhiro, Inoue, Takayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567090/
https://www.ncbi.nlm.nih.gov/pubmed/33060832
http://dx.doi.org/10.1038/s42003-020-01297-2