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Structural basis for activation of the growth hormone-releasing hormone receptor

Growth hormone-releasing hormone (GHRH) regulates the secretion of growth hormone that virtually controls metabolism and growth of every tissue through its binding to the cognate receptor (GHRHR). Malfunction in GHRHR signaling is associated with abnormal growth, making GHRHR an attractive therapeut...

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Detalles Bibliográficos
Autores principales: Zhou, Fulai, Zhang, Huibing, Cong, Zhaotong, Zhao, Li-Hua, Zhou, Qingtong, Mao, Chunyou, Cheng, Xi, Shen, Dan-Dan, Cai, Xiaoqing, Ma, Cheng, Wang, Yuzhe, Dai, Antao, Zhou, Yan, Sun, Wen, Zhao, Fenghui, Zhao, Suwen, Jiang, Hualiang, Jiang, Yi, Yang, Dehua, Eric Xu, H., Zhang, Yan, Wang, Ming-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567103/
https://www.ncbi.nlm.nih.gov/pubmed/33060564
http://dx.doi.org/10.1038/s41467-020-18945-0