Activation of CD8 T cells accelerates anti-PD-1 antibody-induced psoriasis-like dermatitis through IL-6

Use of immune checkpoint inhibitors that target programmed cell death-1 (PD-1) can lead to various autoimmune-related adverse events (irAEs) including psoriasis-like dermatitis. Our observations on human samples indicated enhanced epidermal infiltration of CD8 T cells, and the pathogenesis of which...

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Detalles Bibliográficos
Autores principales: Tanaka, Ryota, Ichimura, Yuki, Kubota, Noriko, Saito, Akimasa, Nakamura, Yoshiyuki, Ishitsuka, Yosuke, Watanabe, Rei, Fujisawa, Yasuhiro, Kanzaki, Mirei, Mizuno, Seiya, Takahashi, Satoru, Fujimoto, Manabu, Okiyama, Naoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567105/
https://www.ncbi.nlm.nih.gov/pubmed/33060784
http://dx.doi.org/10.1038/s42003-020-01308-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567105/
https://www.ncbi.nlm.nih.gov/pubmed/33060784
http://dx.doi.org/10.1038/s42003-020-01308-2

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