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A subset of microRNAs in the Dlk1‐Dio3 cluster regulates age‐associated muscle atrophy by targeting Atrogin‐1

BACKGROUND: The microRNAs (miRNAs) down‐regulated in aged mouse skeletal muscle were mainly clustered within the delta‐like homologue 1 and the type III iodothyronine deiodinase (Dlk1‐Dio3) genomic region. Although clustered miRNAs are coexpressed and regulate multiple targets in a specific signalli...

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Detalles Bibliográficos
Autores principales: Shin, Yeo Jin, Kwon, Eun‐Soo, Lee, Seung‐Min, Kim, Seon‐Kyu, Min, Kyung‐Won, Lim, Jae‐Young, Lee, Bora, Kang, Jae Sook, Kwak, Ju Yeon, Son, Young Hoon, Choi, Jeong Yi, Yang, Yong Ryul, Kim, Seokho, Kim, Yeon‐Soo, Jang, Hak C., Suh, Yousin, Yoon, Je‐Hyun, Lee, Kwang‐Pyo, Kwon, Ki‐Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567143/
https://www.ncbi.nlm.nih.gov/pubmed/32495509
http://dx.doi.org/10.1002/jcsm.12578