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A subset of microRNAs in the Dlk1‐Dio3 cluster regulates age‐associated muscle atrophy by targeting Atrogin‐1
BACKGROUND: The microRNAs (miRNAs) down‐regulated in aged mouse skeletal muscle were mainly clustered within the delta‐like homologue 1 and the type III iodothyronine deiodinase (Dlk1‐Dio3) genomic region. Although clustered miRNAs are coexpressed and regulate multiple targets in a specific signalli...
Autores principales: | Shin, Yeo Jin, Kwon, Eun‐Soo, Lee, Seung‐Min, Kim, Seon‐Kyu, Min, Kyung‐Won, Lim, Jae‐Young, Lee, Bora, Kang, Jae Sook, Kwak, Ju Yeon, Son, Young Hoon, Choi, Jeong Yi, Yang, Yong Ryul, Kim, Seokho, Kim, Yeon‐Soo, Jang, Hak C., Suh, Yousin, Yoon, Je‐Hyun, Lee, Kwang‐Pyo, Kwon, Ki‐Sun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567143/ https://www.ncbi.nlm.nih.gov/pubmed/32495509 http://dx.doi.org/10.1002/jcsm.12578 |
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