Inhibitory Effect of Eslicarbazepine Acetate and S-Licarbazepine on Na(v)1.5 Channels

Eslicarbazepine acetate (ESL) is a dibenzazepine anticonvulsant approved as adjunctive treatment for partial-onset epileptic seizures. Following first pass hydrolysis of ESL, S-licarbazepine (S-Lic) represents around 95% of circulating active metabolites. S-Lic is the main enantiomer responsible for...

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Detalles Bibliográficos
Autores principales: Leslie, Theresa K., Brückner, Lotte, Chawla, Sangeeta, Brackenbury, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567166/
https://www.ncbi.nlm.nih.gov/pubmed/33123007
http://dx.doi.org/10.3389/fphar.2020.555047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567166/
https://www.ncbi.nlm.nih.gov/pubmed/33123007
http://dx.doi.org/10.3389/fphar.2020.555047

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