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Differential cross-seeding properties of tau and α-synuclein in mouse models of tauopathy and synucleinopathy

Co-occurrence of tau and α-synuclein pathologies in a subset of Alzheimer’s disease patients has led to the idea that mixed pathologies may play a unique characteristic role in the Alzheimer’s disease neurodegenerative cascade. To understand the aetiology of such mixed pathologies, we investigated c...

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Detalles Bibliográficos
Autores principales: Williams, Tosha, Sorrentino, Zachary, Weinrich, Mary, Giasson, Benoit I, Chakrabarty, Paramita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567170/
https://www.ncbi.nlm.nih.gov/pubmed/33094280
http://dx.doi.org/10.1093/braincomms/fcaa090