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Functional recreation of age-related CD8 T cells in young mice identifies drivers of aging- and human-specific tissue pathology

Mitigating effects of aging on human health remains elusive because aging impacts multiple systems simultaneously, and because experimental animals exhibit critical aging differences relative to humans. Separation of aging into discrete processes may identify targetable drivers of pathology, particu...

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Detalles Bibliográficos
Autores principales: Panwar, Akanksha, Jhun, Michelle, Rentsendorj, Altan, Mardiros, Armen, Cordner, Ryan, Birch, Kurtis, Yeager, Nicole, Duvall, Gretchen, Golchian, David, Koronyo-Hamaoui, Maya, Cohen, Robert M., Ley, Eric, Black, Keith L., Wheeler, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567339/
https://www.ncbi.nlm.nih.gov/pubmed/32910956
http://dx.doi.org/10.1016/j.mad.2020.111351