Aldose reductase inhibitor form Cassia glauca: A comparative study of cytotoxic activity with Ag nanoparticles (NPs) and molecular docking evaluation

UPLC-MS/MS profiling of Cassia glauca leaves extract revealed the identification of 10 flavonoids. Kaempferol 3-O-β-D-rutinoside was isolated and studied for its cytotoxic activity. It showed high cytotoxic effects against MCF-7 (IC(50) of 4.6±0.038 μg/ml) and HepG-2 (IC(50) of 8.2±0.024 μg/ml) canc...

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Detalles Bibliográficos
Autores principales: Osman, Samir M., Ayoub, Nahla A., Hafez, Safaa A., Ibrahim, Haitham A., El Raey, Mohamed A., El-Emam, Soad Z., Seada, Ahmed A., Saadeldeen, Amr M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567391/
https://www.ncbi.nlm.nih.gov/pubmed/33064762
http://dx.doi.org/10.1371/journal.pone.0240856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567391/
https://www.ncbi.nlm.nih.gov/pubmed/33064762
http://dx.doi.org/10.1371/journal.pone.0240856

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