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Differential Effects of Voclosporin and Tacrolimus on Insulin Secretion From Human Islets

The incidence of new onset diabetes after transplant (NODAT) has increased over the past decade, likely due to calcineurin inhibitor–based immunosuppressants, including tacrolimus (TAC) and cyclosporin. Voclosporin (VCS), a next-generation calcineurin inhibitor, is reported to cause fewer incidences...

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Detalles Bibliográficos
Autores principales: Kolic, Jelena, Beet, Leanne, Overby, Peter, Cen, Haoning Howard, Panzhinskiy, Evgeniy, Ure, Daren R, Cross, Jennifer L, Huizinga, Robert B, Johnson, James D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567406/
https://www.ncbi.nlm.nih.gov/pubmed/32894758
http://dx.doi.org/10.1210/endocr/bqaa162