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The p53 family reaches the final frontier: the variegated regulation of the dark matter of the genome by the p53 family in cancer
The tumour suppressor p53 and its paralogues, p63 and p73, are essential to maintain cellular homoeostasis and the integrity of the cell’s genetic material, thus meriting the title of ‘guardians of the genome’. The p53 family members are transcription factors and fulfill their activities by controll...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567494/ https://www.ncbi.nlm.nih.gov/pubmed/31910062 http://dx.doi.org/10.1080/15476286.2019.1710054 |