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Pharmacokinetics and Bioequivalence of Two Formulations of Valsartan 80 mg Capsules: A Randomized, Single Dose, 4-Period Crossover Study in Healthy Chinese Volunteers Under Fasting and Fed Conditions

PURPOSE: To compare the bioequivalence of two formulations of valsartan (80 mg capsules) under fasting and fed conditions in healthy Chinese volunteers using a full-replicate study design. METHODS: A total of 78 Subjects were randomly assigned to fasting cohort (n = 48) or fed cohort (n = 30). Each...

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Detalles Bibliográficos
Autores principales: Wu, Qingqing, Wang, Xiaodong, Chen, Qian, Zou, Yang, Xu, Xiaoyan, Li, Tingting, Yu, Chen, Zhu, Fu, Zhang, Kanyin E, Jia, Jingying, Liu, Yanmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567554/
https://www.ncbi.nlm.nih.gov/pubmed/33116410
http://dx.doi.org/10.2147/DDDT.S253078