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Atrophy associated with tau pathology precedes overt cell death in a mouse model of progressive tauopathy
Tau pathology in Alzheimer’s disease (AD) first develops in the entorhinal cortex (EC), then spreads to the hippocampus, followed by the neocortex. Overall, tau pathology correlates well with neurodegeneration and cell loss, but the spatial and temporal association between tau pathology and overt vo...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567584/ https://www.ncbi.nlm.nih.gov/pubmed/33067235 http://dx.doi.org/10.1126/sciadv.abc8098 |