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Atrophy associated with tau pathology precedes overt cell death in a mouse model of progressive tauopathy

Tau pathology in Alzheimer’s disease (AD) first develops in the entorhinal cortex (EC), then spreads to the hippocampus, followed by the neocortex. Overall, tau pathology correlates well with neurodegeneration and cell loss, but the spatial and temporal association between tau pathology and overt vo...

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Detalles Bibliográficos
Autores principales: Fung, Christine W., Guo, Jia, Fu, Hongjun, Figueroa, Helen Y., Konofagou, Elisa E., Duff, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567584/
https://www.ncbi.nlm.nih.gov/pubmed/33067235
http://dx.doi.org/10.1126/sciadv.abc8098

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