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A Flexible, Pooled CRISPR Library for Drug Development Screens

Functional genomic screening with CRISPR has provided a powerful and precise new way to interrogate the phenotypic consequences of gene manipulation in high-throughput, unbiased analyses. However, some experimental paradigms prove especially challenging and require carefully and appropriately adapte...

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Detalles Bibliográficos
Autores principales: Blanck, Maximilian, Budnik-Zawilska, Milka B., Lenger, Steven R., McGonigle, John E., Martin, Glynn R.A., le Sage, Carlos, Lawo, Steffen, Pemberton, Helen N., Tiwana, Gaganpreet S., Sorrell, David A., Cross, Benedict C.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567641/
https://www.ncbi.nlm.nih.gov/pubmed/33054419
http://dx.doi.org/10.1089/crispr.2019.0066