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Regional [(18)F]flortaucipir PET is more closely associated with disease severity than CSF p-tau in Alzheimer’s disease

PURPOSE: In vivo Alzheimer’s disease (AD) biomarkers for tau pathology are cerebrospinal fluid (CSF) phosphorylated tau (p-tau) and [(18)F]flortaucipir positron emission tomography (PET). Our aim was to assess associations between CSF p-tau with [(18)F]flortaucipir PET and the associations of both t...

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Detalles Bibliográficos
Autores principales: Wolters, Emma E., Ossenkoppele, Rik, Verfaillie, Sander C. J., Coomans, Emma M., Timmers, Tessa, Visser, Denise, Tuncel, Hayel, Golla, Sandeep S. V., Windhorst, Albert D., Boellaard, Ronald, van der Flier, Wiesje M., Teunissen, Charlotte E., Scheltens, Philip, van Berckel, Bart N. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567681/
https://www.ncbi.nlm.nih.gov/pubmed/32291510
http://dx.doi.org/10.1007/s00259-020-04758-2