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Quantitative Proteomics Analysis of Lytic KSHV Infection in Human Endothelial Cells Reveals Targets of Viral Immune Modulation

Kaposi’s sarcoma herpesvirus (KSHV) is an oncogenic human virus and the leading cause of mortality in HIV infection. KSHV reactivation from latent- to lytic-stage infection initiates a cascade of viral gene expression. Here we show how these changes remodel the host cell proteome to enable viral rep...

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Detalles Bibliográficos
Autores principales: Gabaev, Ildar, Williamson, James C., Crozier, Thomas W.M., Schulz, Thomas F., Lehner, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567700/
https://www.ncbi.nlm.nih.gov/pubmed/33053346
http://dx.doi.org/10.1016/j.celrep.2020.108249