Cargando…

Quantitative Proteomics Analysis of Lytic KSHV Infection in Human Endothelial Cells Reveals Targets of Viral Immune Modulation

Kaposi’s sarcoma herpesvirus (KSHV) is an oncogenic human virus and the leading cause of mortality in HIV infection. KSHV reactivation from latent- to lytic-stage infection initiates a cascade of viral gene expression. Here we show how these changes remodel the host cell proteome to enable viral rep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gabaev, Ildar, Williamson, James C., Crozier, Thomas W.M., Schulz, Thomas F., Lehner, Paul J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2020
Materias:	Resource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567700/ https://www.ncbi.nlm.nih.gov/pubmed/33053346 http://dx.doi.org/10.1016/j.celrep.2020.108249

Ejemplares similares

A Temporal Proteomic Map of Epstein-Barr Virus Lytic Replication in B Cells
por: Ersing, Ina, et al.
Publicado: (2017)

KSHV Targeted Therapy: An Update on Inhibitors of Viral Lytic Replication
por: Coen, Natacha, et al.
Publicado: (2014)

Kaposi’s Sarcoma-Associated Herpesvirus Lytic Replication Is Independent of Anaphase-Promoting Complex Activity
por: Elbasani, Endrit, et al.
Publicado: (2020)

Molecular Biology of KSHV Lytic Reactivation
por: Purushothaman, Pravinkumar, et al.
Publicado: (2015)

Regulation of KSHV Latency and Lytic Reactivation
por: Broussard, Grant, et al.
Publicado: (2020)

Transient induction of lytic Kaposi's sarcoma-associated herpesvirus (KSHV) genes in KSHV-infected endothelial cells exposed to hypoxia
por: Velasco, P, et al.
Publicado: (2009)

A Quantitative Proteomic Analysis of Hemogenic Endothelium Reveals Differential Regulation of Hematopoiesis by SOX17
por: Clarke, Raedun L., et al.
Publicado: (2015)

Epigenetic Analysis of KSHV Latent and Lytic Genomes
por: Toth, Zsolt, et al.
Publicado: (2010)

RSK-c-Fos in KSHV lytic progression
por: Li, Xiaojuan, et al.
Publicado: (2015)

Contribution of the KSHV and EBV lytic cycles to tumourigenesis
por: Manners, Oliver, et al.
Publicado: (2018)

KSHV lytic proteins K-RTA and K8 bind to cellular and viral chromatin to modulate gene expression
por: Kaul, Rajeev, et al.
Publicado: (2019)

Quantitative Map of Proteome Dynamics during Neuronal Differentiation
por: Frese, Christian K., et al.
Publicado: (2017)

A Viral Genome Landscape of RNA Polyadenylation from KSHV Latent to Lytic Infection
por: Majerciak, Vladimir, et al.
Publicado: (2013)

Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale
por: Morgenstern, Marcel, et al.
Publicado: (2017)

RSK1 SUMOylation is required for KSHV lytic replication
por: Liu, Zhenshan, et al.
Publicado: (2021)

Quantitative Analysis of Fission Yeast Transcriptomes and Proteomes in Proliferating and Quiescent Cells
por: Marguerat, Samuel, et al.
Publicado: (2012)

Quantitative analysis of human centrosome architecture by targeted proteomics and fluorescence imaging
por: Bauer, Manuel, et al.
Publicado: (2016)

Abortive Lytic Reactivation of KSHV in CBF1/CSL Deficient Human B Cell Lines
por: Scholz, Barbara A., et al.
Publicado: (2013)

Quantitative Analysis of Human Pluripotency and Neural Specification by In-Depth (Phospho)Proteomic Profiling
por: Singec, Ilyas, et al.
Publicado: (2016)

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context
por: Morgenstern, Marcel, et al.
Publicado: (2021)

Clinical Manifestations of Kaposi Sarcoma Herpesvirus Lytic Activation: Multicentric Castleman Disease (KSHV–MCD) and the KSHV Inflammatory Cytokine Syndrome
por: Polizzotto, Mark N., et al.
Publicado: (2012)

ADAR1 Facilitates KSHV Lytic Reactivation by Modulating the RLR-Dependent Signaling Pathway
por: Zhang, Huirong, et al.
Publicado: (2020)

Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion
por: Crozier, Thomas W.M., et al.
Publicado: (2022)

An optimized quantitative proteomics method establishes the cell type‐resolved mouse brain secretome
por: Tüshaus, Johanna, et al.
Publicado: (2020)

Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ
por: Cappelletti, Valentina, et al.
Publicado: (2021)

Corrigendum: Clinical manifestations of Kaposi sarcoma herpesvirus lytic activation: multicentric Castleman disease (KSHV–MCD) and the KSHV inflammatory cytokine syndrome
por: Polizzotto, Mark N., et al.
Publicado: (2017)

The activation of KSHV lytic cycle blocks autophagy in PEL cells
por: Granato, Marisa, et al.
Publicado: (2015)

The landscape of transcription initiation across latent and lytic KSHV genomes
por: Ye, Xiang, et al.
Publicado: (2019)

KSHV ORF59 and PAN RNA Recruit Histone Demethylases to the Viral Chromatin during Lytic Reactivation
por: Hiura, Kayla, et al.
Publicado: (2020)

Spatial and proteomic profiling reveals centrosome‐independent features of centriolar satellites
por: Gheiratmand, Ladan, et al.
Publicado: (2019)

Epigenetic factor siRNA screen during primary KSHV infection identifies novel host restriction factors for the lytic cycle of KSHV
por: Naik, Nenavath Gopal, et al.
Publicado: (2020)

Host Transcript Accumulation during Lytic KSHV Infection Reveals Several Classes of Host Responses
por: Chandriani, Sanjay, et al.
Publicado: (2007)

A Thermodynamic Atlas of Proteomes Reveals Energetic Innovation across the Tree of Life
por: Chin, Alexander F, et al.
Publicado: (2022)

Comparative membrane proteomics reveals diverse cell regulators concentrated at the nuclear envelope
por: Cheng, Li-Chun, et al.
Publicado: (2023)

The Kaposi's sarcoma-associated herpesvirus (KSHV) non-structural membrane protein K15 is required for viral lytic replication and may represent a therapeutic target
por: Abere, Bizunesh, et al.
Publicado: (2017)

Quantitative Temporal Viromics: An Approach to Investigate Host-Pathogen Interaction
por: Weekes, Michael P., et al.
Publicado: (2014)

Global mitochondrial protein import proteomics reveal distinct regulation by translation and translocation machinery
por: Schäfer, Jasmin Adriana, et al.
Publicado: (2022)

Activation of DNA Damage Response Pathways during Lytic Replication of KSHV
por: Hollingworth, Robert, et al.
Publicado: (2015)

KSHV Reactivation and Novel Implications of Protein Isomerization on Lytic Switch Control
por: Guito, Jonathan, et al.
Publicado: (2015)

Efficient lytic induction of kaposi's sarcoma-associated herpesvirus (KSHV) by the anthracyclines
por: Kang, Hyunju, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_0omb5i132m74gd89kn3qo77kkf