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Photoreactivity of Bis-retinoid A2E Complexed with a Model Protein in Selected Model Systems
The bis-retinoid N-retinyl-N-retinylidene ethanolamine (A2E) is formed as a byproduct of visual cycle in retinal pigment epithelium (RPE). It contributes to golden-yellow fluorescence of the age pigment lipofuscin, which accumulates in RPE. Lipofuscin can generate a variety of reactive oxygen specie...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567710/ https://www.ncbi.nlm.nih.gov/pubmed/32920760 http://dx.doi.org/10.1007/s12013-020-00942-1 |