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Photoreactivity of Bis-retinoid A2E Complexed with a Model Protein in Selected Model Systems

The bis-retinoid N-retinyl-N-retinylidene ethanolamine (A2E) is formed as a byproduct of visual cycle in retinal pigment epithelium (RPE). It contributes to golden-yellow fluorescence of the age pigment lipofuscin, which accumulates in RPE. Lipofuscin can generate a variety of reactive oxygen specie...

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Detalles Bibliográficos
Autores principales: Furso, Justyna, Zadlo, Andrzej, Szewczyk, Grzegorz, Sarna, Tadeusz J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567710/
https://www.ncbi.nlm.nih.gov/pubmed/32920760
http://dx.doi.org/10.1007/s12013-020-00942-1