GPAHex-A synthetic biology platform for Type IV–V glycopeptide antibiotic production and discovery

Glycopeptide antibiotics (GPAs) are essential for the treatment of severe infectious diseases caused by Gram-positive bacteria. The emergence and spread of GPA resistance have propelled the search for more effective GPAs. Given their structural complexity, genetic intractability, and low titer, expa...

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Detalles Bibliográficos
Autores principales: Xu, Min, Wang, Wenliang, Waglechner, Nicholas, Culp, Elizabeth J., Guitor, Allison K., Wright, Gerard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567792/
https://www.ncbi.nlm.nih.gov/pubmed/33067466
http://dx.doi.org/10.1038/s41467-020-19138-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567792/
https://www.ncbi.nlm.nih.gov/pubmed/33067466
http://dx.doi.org/10.1038/s41467-020-19138-5

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