Cargando…
GPAHex-A synthetic biology platform for Type IV–V glycopeptide antibiotic production and discovery
Glycopeptide antibiotics (GPAs) are essential for the treatment of severe infectious diseases caused by Gram-positive bacteria. The emergence and spread of GPA resistance have propelled the search for more effective GPAs. Given their structural complexity, genetic intractability, and low titer, expa...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567792/ https://www.ncbi.nlm.nih.gov/pubmed/33067466 http://dx.doi.org/10.1038/s41467-020-19138-5 |