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Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ

The alternative non-homologous end-joining (NHEJ) pathway promotes DNA double-strand break (DSB) repair in cells deficient for NHEJ or homologous recombination, suggesting that it operates at all stages of the cell cycle. Here, we use an approach in which DNA breaks can be induced in G1 cells and th...

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Detalles Bibliográficos
Autores principales: Yu, Wei, Lescale, Chloé, Babin, Loelia, Bedora-Faure, Marie, Lenden-Hasse, Hélène, Baron, Ludivine, Demangel, Caroline, Yelamos, José, Brunet, Erika, Deriano, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567796/
https://www.ncbi.nlm.nih.gov/pubmed/33067475
http://dx.doi.org/10.1038/s41467-020-19060-w