Cargando…

Detection of haplotype-dependent allele-specific DNA methylation in WGBS data

In heterozygous genomes, allele-specific measurements can reveal biologically significant differences in DNA methylation between homologous alleles associated with local changes in genetic sequence. Current approaches for detecting such events from whole-genome bisulfite sequencing (WGBS) data perfo...

Descripción completa

Detalles Bibliográficos
Autores principales: Abante, J., Fang, Y., Feinberg, A. P., Goutsias, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567826/
https://www.ncbi.nlm.nih.gov/pubmed/33067439
http://dx.doi.org/10.1038/s41467-020-19077-1