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Detection of haplotype-dependent allele-specific DNA methylation in WGBS data
In heterozygous genomes, allele-specific measurements can reveal biologically significant differences in DNA methylation between homologous alleles associated with local changes in genetic sequence. Current approaches for detecting such events from whole-genome bisulfite sequencing (WGBS) data perfo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567826/ https://www.ncbi.nlm.nih.gov/pubmed/33067439 http://dx.doi.org/10.1038/s41467-020-19077-1 |