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Cryo-electron tomography of cardiac myofibrils reveals a 3D lattice spring within the Z-discs

The Z-disc forms a boundary between sarcomeres, which constitute structural and functional units of striated muscle tissue. Actin filaments from adjacent sarcomeres are cross-bridged by α-actinin in the Z-disc, allowing transmission of tension across the myofibril. Despite decades of studies, the 3D...

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Detalles Bibliográficos
Autores principales: Oda, Toshiyuki, Yanagisawa, Haruaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567829/
https://www.ncbi.nlm.nih.gov/pubmed/33067529
http://dx.doi.org/10.1038/s42003-020-01321-5