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Cryo-electron tomography of cardiac myofibrils reveals a 3D lattice spring within the Z-discs
The Z-disc forms a boundary between sarcomeres, which constitute structural and functional units of striated muscle tissue. Actin filaments from adjacent sarcomeres are cross-bridged by α-actinin in the Z-disc, allowing transmission of tension across the myofibril. Despite decades of studies, the 3D...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567829/ https://www.ncbi.nlm.nih.gov/pubmed/33067529 http://dx.doi.org/10.1038/s42003-020-01321-5 |