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BioID-based proteomic analysis of the Bid interactome identifies novel proteins involved in cell-cycle-dependent apoptotic priming

Apoptotic priming controls the commitment of cells to apoptosis by determining how close they lie to mitochondrial permeabilisation. Variations in priming are important for how both healthy and cancer cells respond to chemotherapeutic agents, but how it is dynamically coordinated by Bcl-2 proteins r...

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Detalles Bibliográficos
Autores principales: Pedley, Robert, King, Louise E., Mallikarjun, Venkatesh, Wang, Pengbo, Swift, Joe, Brennan, Keith, Gilmore, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567853/
https://www.ncbi.nlm.nih.gov/pubmed/33067418
http://dx.doi.org/10.1038/s41419-020-03091-8