New insights on human IRE1 tetramer structures based on molecular modeling

Inositol-Requiring Enzyme 1α (IRE1α; hereafter IRE1) is a transmembrane kinase/ribonuclease protein related with the unfolded protein response (UPR) signaling. Experimental evidence suggests that IRE1 forms several three dimensional (3D) structural variants: dimers, tetramers and higher order oligom...

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Detalles Bibliográficos
Autores principales: Carlesso, Antonio, Hörberg, Johanna, Reymer, Anna, Eriksson, Leif A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567888/
https://www.ncbi.nlm.nih.gov/pubmed/33060689
http://dx.doi.org/10.1038/s41598-020-74347-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567888/
https://www.ncbi.nlm.nih.gov/pubmed/33060689
http://dx.doi.org/10.1038/s41598-020-74347-8

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