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Synthesis, density functional theory (DFT) studies and urease inhibition activity of chiral benzimidazoles

A variety of benzimidazole by the heterocyclization of orthophenylenediamine were synthesized in 69–86% yields. The synthesized compounds 3a-f and 6a-f were characterized and further investigated as jack bean urease inhibitors. Density functional theory (DFT) studies were performed utilizing the bas...

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Detalles Bibliográficos
Autores principales: Aman, Hasil, Rashid, Naghmana, Ashraf, Zaman, Bibi, Aamna, Chen, Hsin-Tsung, Sathishkumar, Nadaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567930/
https://www.ncbi.nlm.nih.gov/pubmed/33088954
http://dx.doi.org/10.1016/j.heliyon.2020.e05187