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Synthesis, density functional theory (DFT) studies and urease inhibition activity of chiral benzimidazoles
A variety of benzimidazole by the heterocyclization of orthophenylenediamine were synthesized in 69–86% yields. The synthesized compounds 3a-f and 6a-f were characterized and further investigated as jack bean urease inhibitors. Density functional theory (DFT) studies were performed utilizing the bas...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567930/ https://www.ncbi.nlm.nih.gov/pubmed/33088954 http://dx.doi.org/10.1016/j.heliyon.2020.e05187 |