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Δ42PD1-TLR4 Augments γδ-T Cell Activation of the Transitional Memory Subset of CD4(+) T Cells

TLR ligands can contribute to T cell immune responses by indirectly stimulating antigen presentation and cytokines and directly serving as co-stimulatory signals. We have previously reported that the human endogenous surface protein, Δ42PD1, is expressed primarily on (Vγ9)Vδ2 cells and can interact...

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Detalles Bibliográficos
Autores principales: Mo, Yufei, Cheung, Allen Ka Loon, Liu, Yue, Liu, Li, Chen, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567942/
https://www.ncbi.nlm.nih.gov/pubmed/33089108
http://dx.doi.org/10.1016/j.isci.2020.101620