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Rh-CSF1 Attenuates Oxidative Stress and Neuronal Apoptosis via the CSF1R/PLCG2/PKA/UCP2 Signaling Pathway in a Rat Model of Neonatal HIE

Oxidative stress (OS) and neuronal apoptosis are major pathological processes after hypoxic-ischemic encephalopathy (HIE). Colony stimulating factor 1 (CSF1), binding to CSF1 receptor (CSF1R), has been shown to reduce neuronal loss after hypoxic-ischemia- (HI-) induced brain injury. In the present s...

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Detalles Bibliográficos
Autores principales: Hu, Xiao, Li, Shirong, Doycheva, Desislava Met, Huang, Lei, Lenahan, Cameron, Liu, Rui, Huang, Juan, Gao, Ling, Tang, Jiping, Zuo, Gang, Zhang, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568161/
https://www.ncbi.nlm.nih.gov/pubmed/33101590
http://dx.doi.org/10.1155/2020/6801587