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iRHOM2: A Regulator of Palmoplantar Biology, Inflammation, and Viral Susceptibility

The palmoplantar epidermis is a specialized area of the skin that undergoes high levels of mechanical stress. The palmoplantar keratinization and esophageal cancer syndrome, tylosis with esophageal cancer, is linked to mutations in RHBDF2 encoding the proteolytically inactive rhomboid protein, iRhom...

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Detalles Bibliográficos
Autores principales: Chao-Chu, Jennifer, Murtough, Stephen, Zaman, Najwa, Pennington, Daniel J., Blaydon, Diana C., Kelsell, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier, Inc. on behalf of the Society for Investigative Dermatology. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568177/
https://www.ncbi.nlm.nih.gov/pubmed/33080304
http://dx.doi.org/10.1016/j.jid.2020.09.010