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Naught all zeros in sequence count data are the same

Genomic studies feature multivariate count data from high-throughput DNA sequencing experiments, which often contain many zero values. These zeros can cause artifacts for statistical analyses and multiple modeling approaches have been developed in response. Here, we apply different zero-handling mod...

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Detalles Bibliográficos
Autores principales: Silverman, Justin D., Roche, Kimberly, Mukherjee, Sayan, David, Lawrence A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568192/
https://www.ncbi.nlm.nih.gov/pubmed/33101615
http://dx.doi.org/10.1016/j.csbj.2020.09.014