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Converting Escherichia coli MG1655 into a chemical overproducer through inactivating defense system against exogenous DNA

Escherichia coli strain K-12 MG1655 has been proposed as an appropriate host strain for industrial production. However, the direct application of this strain suffers from the transformation inefficiency and plasmid instability. Herein, we conducted genetic modifications at a serial of loci of MG1655...

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Detalles Bibliográficos
Autores principales: Wang, Jingge, Huang, Chaoyong, Guo, Kai, Ma, Lianjie, Meng, Xiangyu, Wang, Ning, Huo, Yi-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568196/
https://www.ncbi.nlm.nih.gov/pubmed/33102829
http://dx.doi.org/10.1016/j.synbio.2020.10.005