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Converting Escherichia coli MG1655 into a chemical overproducer through inactivating defense system against exogenous DNA
Escherichia coli strain K-12 MG1655 has been proposed as an appropriate host strain for industrial production. However, the direct application of this strain suffers from the transformation inefficiency and plasmid instability. Herein, we conducted genetic modifications at a serial of loci of MG1655...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568196/ https://www.ncbi.nlm.nih.gov/pubmed/33102829 http://dx.doi.org/10.1016/j.synbio.2020.10.005 |