Nuclear receptor REVERBα is a state-dependent regulator of liver energy metabolism

The nuclear receptor REVERBα is a core component of the circadian clock and proposed to be a dominant regulator of hepatic lipid metabolism. Using antibody-independent ChIP-sequencing of REVERBα in mouse liver, we reveal a high-confidence cistrome and define direct target genes. REVERBα-binding site...

Descripción completa

Detalles Bibliográficos
Autores principales: Hunter, A. Louise, Pelekanou, Charlotte E., Adamson, Antony, Downton, Polly, Barron, Nichola J., Cornfield, Thomas, Poolman, Toryn M., Humphreys, Neil, Cunningham, Peter S., Hodson, Leanne, Loudon, Andrew S. I., Iqbal, Mudassar, Bechtold, David A., Ray, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568238/
https://www.ncbi.nlm.nih.gov/pubmed/32989157
http://dx.doi.org/10.1073/pnas.2005330117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568238/
https://www.ncbi.nlm.nih.gov/pubmed/32989157
http://dx.doi.org/10.1073/pnas.2005330117

Ejemplares similares