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Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation

Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19 is a newly recognized condition in children with recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. These children and adult patients with severe hyperinflammation present with a constellation...

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Detalles Bibliográficos
Autores principales: Cheng, Mary Hongying, Zhang, She, Porritt, Rebecca A., Noval Rivas, Magali, Paschold, Lisa, Willscher, Edith, Binder, Mascha, Arditi, Moshe, Bahar, Ivet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568239/
https://www.ncbi.nlm.nih.gov/pubmed/32989130
http://dx.doi.org/10.1073/pnas.2010722117