Evaluation of two xenobiotic reductases from Pseudomonas putida for their suitability for magnetic nanoparticle‐directed enzyme prodrug therapy as a novel approach to cancer treatment

Directed enzyme prodrug therapy (DEPT) is a cancer chemotherapy strategy in which bacterial enzymes are delivered to a cancer site before prodrug administration, resulting in prodrug activation at the cancer site and more localized treatment. A major limitation to DEPT is the poor effectiveness of t...

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Detalles Bibliográficos
Autores principales: Ball, Patrick, Halliwell, Jennifer, Anderson, Simon, Gwenin, Vanessa, Gwenin, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568253/
https://www.ncbi.nlm.nih.gov/pubmed/32979040
http://dx.doi.org/10.1002/mbo3.1110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568253/
https://www.ncbi.nlm.nih.gov/pubmed/32979040
http://dx.doi.org/10.1002/mbo3.1110

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