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The role of fibril structure and surface hydrophobicity in secondary nucleation of amyloid fibrils
Crystals, nanoparticles, and fibrils catalyze the generation of new aggregates on their surface from the same type of monomeric building blocks as the parent assemblies. This secondary nucleation process can be many orders of magnitude faster than primary nucleation. In the case of amyloid fibrils a...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568274/ https://www.ncbi.nlm.nih.gov/pubmed/33004626 http://dx.doi.org/10.1073/pnas.2002956117 |