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Epigenome-wide association study of Alzheimer’s disease replicates 22 differentially methylated positions and 30 differentially methylated regions

BACKGROUND: Growing evidence shows that epigenetic modifications play a role in Alzheimer’s disease (AD). We performed an epigenome-wide association study (EWAS) to evaluate the DNA methylation differences using postmortem superior temporal gyrus (STG) and inferior frontal gyrus (IFG) samples. RESUL...

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Detalles Bibliográficos
Autores principales: Li, Qingqin S., Sun, Yu, Wang, Tania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568396/
https://www.ncbi.nlm.nih.gov/pubmed/33069246
http://dx.doi.org/10.1186/s13148-020-00944-z