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Integrated genomics analysis highlights important SNPs and genes implicated in moderate-to-severe asthma based on GWAS and eQTL datasets

BACKGROUND: Severe asthma is a chronic disease contributing to disproportionate disease morbidity and mortality. From the year of 2007, many genome-wide association studies (GWAS) have documented a large number of asthma-associated genetic variants and related genes. Nevertheless, the molecular mech...

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Detalles Bibliográficos
Autores principales: Dong, Zhouzhou, Ma, Yunlong, Zhou, Hua, Shi, Linhui, Ye, Gongjie, Yang, Lei, Liu, Panpan, Zhou, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568423/
https://www.ncbi.nlm.nih.gov/pubmed/33066754
http://dx.doi.org/10.1186/s12890-020-01303-7