Abnormal MGMT Promoter Methylation in Gastrointestinal Stromal Tumors: Genetic Susceptibility and Association with Clinical Outcome

PURPOSE: KIT/PDGFRA wild-type (WT) gastrointestinal stromal tumors (GISTs) represent a heterogeneous subgroup of GISTs that lack KIT or PDGFRA mutations and possess distinct genetic alterations and primary resistance to imatinib. Succinate dehydrogenase (SDH)-deficient GISTs comprise the largest sub...

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Detalles Bibliográficos
Autores principales: Lou, Liping, Zhang, Wendi, Li, Jun, Wang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568426/
https://www.ncbi.nlm.nih.gov/pubmed/33116851
http://dx.doi.org/10.2147/CMAR.S269388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568426/
https://www.ncbi.nlm.nih.gov/pubmed/33116851
http://dx.doi.org/10.2147/CMAR.S269388

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